Our physiological DNA
In 2026, DEMX brought together a modern Japanese philosophy of physiological care and the high standards of Spanish production. We do not invent a new biology — we work with the one the skin already has.
The philosophy of DEMX physiological care is to act in line with skin biology, using active ingredients in substantiated concentrations to reach a predictable, visible result. Epidermis, dermis, hypodermis — each layer gets a clear job in the protocol, then the result is locked with photoprotection.
Technological precision, thoughtful formulas of Japanese development and strict quality control sit at the base of professional performance in every product. That is the Japanese approach to formula design: not more actives, but the right ones, in the right order, at the right pH.
values, indeed
technological precision
Every protocol is a system, not a single jar. CO₂ activation, acids, peptides and SPF are written as steps with a measured pH and a stated REF.
japanese formulas
Japanese development behind each formula: blue exosomes PHORMISKIN™, orchid stem cells Orhistem™, PDRN, Matrixyl®, Replexium™, Argireline®
spanish production
Strict quality control and European manufacturing standards hold the line from lab to cabin. Alginate bases come from TECHNATURE, France.
physiology first
We work with oxygenation (the Bohr effect of CO₂), the barrier, sebum and pigment — then restore lipids so the skin is not left stripped.

science, not sorcery
Carboxytherapy sits at the center of the DEMX cabin. A rise in CO₂ and a fall in pH reduce hemoglobin’s affinity for oxygen, so oxygen is released more easily into peripheral tissue. That is why every system starts with an acid prep and a CO₂ activator, then a mask, then SPF.
three professional systems
blue exosome
Revitalization, firmness, glow. Blue marine exosomes, Replexium™, Neodermyl®, Easyliance™. For dull, stressed, dehydrated skin and first age-related changes.
Around the three systems sit professional cleansing, active serums, functional creams, post-peel and alginate masks, and daily sun protection — so the cabin protocol and the home finish speak the same language.
azelaic renewal
Acne, post-acne, oily and combination skin. Azelaic 10%, AHA 20%, niacinamide, zinc, seven ceramides. Correction without aggressive over-drying.
orchid stem cell
Lift, remodel, revitalize. Orchid stem cells, PDRN, Matrixyl® 3000, Argireline®, copper tripeptide. Density, contours, wrinkles.